HIV Target gene Detail Information

> KCNN1 Gene Search Result

Gene Information

Gene Name	KCNN1
Gene ID	3780
Gene Full Name	potassium calcium-activated channel subfamily N member 1
Gene Alias	SK1; hSK1; SKCA1; KCa2.1
Transcripts	ENSG00000105642
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q92952
HGNC ID	HGNC:6290
VEGA ID	OTTHUMG00000183482
OMIM ID	602982
String ID	9606.ENSP00000476519
Drugbank ID	BE0004425; BE0004906
PharmGKB ID	PA30070

Target gene [KCNN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016702	chr19				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KCNN1 expression and immune infiltrating cell level correlation result in HIV+ samples
KCNN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).