HBV Target gene Detail Information

> KCNMA1 Gene Search Result


Gene Information
Gene Name KCNMA1
Gene ID 3778
Gene Full Name potassium calcium-activated channel subfamily M alpha 1
Gene Alias SLO; BKTM; SLO1; hSlo; MaxiK; PNKD3; SAKCA; mSLO1; CADEDS; KCa1.1; SLO-ALPHA; bA205K10.1
Transcripts ENSG00000156113
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID Q12791
HGNC ID HGNC:6284
VEGA ID OTTHUMG00000018543
OMIM ID 600150
String ID 9606.ENSP00000286628
Drugbank ID BE0000553; BE0004784; BE0004906
PharmGKB ID PA220
Target gene [KCNMA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014152 chr10 4 4 View
1014153 chr10 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNMA1 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNMA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).