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HTLV1 Target gene Detail Information

> KCNK9 Gene Search Result


Gene Information
Gene Name KCNK9
Gene ID 51305
Gene Full Name potassium two pore domain channel subfamily K member 9
Gene Alias KT3.2; TASK3; K2p9.1; TASK-3
Transcripts ENSG00000169427
Virus HTLV1
Gene Type protein coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q9NPC2
HGNC ID HGNC:6283
VEGA ID OTTHUMG00000164186
OMIM ID 605874
String ID 9606.ENSP00000430676
Drugbank ID BE0003583
PharmGKB ID PA30065
Target gene [KCNK9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005159 chr8 77 17 94 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of KCNK9 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK9 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of KCNK9 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK9 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of KCNK9 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK9 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).