HBV Target gene Detail Information

> KCNK3 Gene Search Result

Gene Information

Gene Name	KCNK3
Gene ID	3777
Gene Full Name	potassium two pore domain channel subfamily K member 3
Gene Alias	OAT1; PPH4; TASK; TBAK1; K2p3.1; TASK-1
Transcripts	ENSG00000171303
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	O14649
HGNC ID	HGNC:6278
VEGA ID	OTTHUMG00000125530
OMIM ID	603220
String ID	9606.ENSP00000306275
Drugbank ID	BE0003582
PharmGKB ID	PA30060

Target gene [KCNK3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003165	chr2	31	17	111	159	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNK3 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNK3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).