HTLV1 Target gene Detail Information

> KCNK15 Gene Search Result

Gene Information

Gene Name	KCNK15
Gene ID	60598
Gene Full Name	potassium two pore domain channel subfamily K member 15
Gene Alias	KT3.3; TASK5; KCNK11; KCNK14; TASK-5; K2p15.1; dJ781B1.1
Transcripts	ENSG00000124249
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q9H427
HGNC ID	HGNC:13814
VEGA ID	OTTHUMG00000032544
OMIM ID	607368
String ID	9606.ENSP00000361952
PharmGKB ID	PA30056

Target gene [KCNK15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003030	chr20	56	125	7	188	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KCNK15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK15 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of KCNK15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK15 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of KCNK15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNK15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).