HBV Target gene Detail Information

> KCNJ3 Gene Search Result

Gene Information

Gene Name	KCNJ3
Gene ID	3760
Gene Full Name	potassium voltage-gated channel subfamily J member 3
Gene Alias	KGA; GIRK1; KIR3.1
Transcripts	ENSG00000162989
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	P48549
HGNC ID	HGNC:6264
VEGA ID	OTTHUMG00000131937
OMIM ID	601534
String ID	9606.ENSP00000295101
Drugbank ID	BE0001028
PharmGKB ID	PA215

Target gene [KCNJ3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002328	chr2	32	237	24	293	View
1002340	chr2	33	233	24	290	View
1400539	chr2	41	1	3	45	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNJ3 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNJ3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).