HBV Target gene Detail Information

> KCNH8 Gene Search Result


Gene Information
Gene Name KCNH8
Gene ID 131096
Gene Full Name potassium voltage-gated channel subfamily H member 8
Gene Alias ELK; ELK1; elk3; Kv12.1
Transcripts ENSG00000183960
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID Q96L42
HGNC ID HGNC:18864
VEGA ID OTTHUMG00000129891
OMIM ID 608260
String ID 9606.ENSP00000328813
Drugbank ID BE0010062; BE0009847
PharmGKB ID PA38724
Target gene [KCNH8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006479 chr3 38 38 View
1400473 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNH8 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNH8 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).