HIV Target gene Detail Information

> KCNH7 Gene Search Result

Gene Information

Gene Name	KCNH7
Gene ID	90134
Gene Full Name	potassium voltage-gated channel subfamily H member 7
Gene Alias	ERG3; HERG3; Kv11.3
Transcripts	ENSG00000184611
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q9NS40
HGNC ID	HGNC:18863
VEGA ID	OTTHUMG00000132069
OMIM ID	608169
String ID	9606.ENSP00000331727
Drugbank ID	BE0000699; BE0009629; BE0009847
PharmGKB ID	PA38723

Target gene [KCNH7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011232	chr2	3	3	1	7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KCNH7 expression and immune infiltrating cell level correlation result in HIV+ samples
KCNH7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).