HBV Target gene Detail Information

> KCNH5 Gene Search Result

Gene Information

Gene Name	KCNH5
Gene ID	27133
Gene Full Name	potassium voltage-gated channel subfamily H member 5
Gene Alias	EAG2; hEAG2; H-EAG2; Kv10.2
Transcripts	ENSG00000140015
Virus	HBV
Gene Type	protein coding
HPA Location Info	Centrosome;Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q8NCM2
HGNC ID	HGNC:6254
VEGA ID	OTTHUMG00000029041
OMIM ID	605716
String ID	9606.ENSP00000321427
Drugbank ID	BE0010041; BE0009847
PharmGKB ID	PA30040

Target gene [KCNH5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007381	chr14	26		2	28	View
1011083	chr14	9	1		10	View
1017626	chr14				0	View
1401683	chr14				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNH5 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNH5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).