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HBV Target gene Detail Information

> KCNH1 Gene Search Result


Gene Information
Gene Name KCNH1
Gene ID 3756
Gene Full Name potassium voltage-gated channel subfamily H member 1
Gene Alias EAG; EAG1; ZLS1; TMBTS; h-eag; hEAG1; Kv10.1
Transcripts ENSG00000143473
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID O95259
HGNC ID HGNC:6250
VEGA ID OTTHUMG00000036309
OMIM ID 603305
String ID 9606.ENSP00000271751
Drugbank ID BE0005116; BE0005191; BE0009847
PharmGKB ID PA30037
Target gene [KCNH1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000464 chr1 1586 1058 492 3136 View
1000465 chr1 1586 1058 492 3136 View
1004112 chr1 83 13 1 97 View
1004113 chr1 83 13 1 97 View
1004646 chr1 64 10 74 View
1005253 chr1 48 10 58 View
1005468 chr1 50 4 54 View
1005852 chr1 45 2 47 View
1008881 chr1 17 2 19 View
1009068 chr1 17 1 18 View
1010809 chr1 10 1 11 View
1012478 chr1 6 6 View
1017492 chr1 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNH1 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNH1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).