HBV Target gene Detail Information

> KCND2 Gene Search Result

Gene Information

Gene Name	KCND2
Gene ID	3751
Gene Full Name	potassium voltage-gated channel subfamily D member 2
Gene Alias	RK5; KV4.2
Transcripts	ENSG00000184408
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q9NZV8
HGNC ID	HGNC:6238
VEGA ID	OTTHUMG00000156989
OMIM ID	605410
String ID	9606.ENSP00000333496
Drugbank ID	BE0003603; BE0009847
PharmGKB ID	PA30030

Target gene [KCND2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005172	chr7	9	28	23	60	View
1006971	chr7	3	23	6	32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCND2 expression and immune infiltrating cell level correlation result in HBV+ samples
KCND2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).