HIV Target gene Detail Information

> KCNC4 Gene Search Result


Gene Information
Gene Name KCNC4
Gene ID 3749
Gene Full Name potassium voltage-gated channel subfamily C member 4
Gene Alias KV3.4; C1orf30; KSHIIIC; HKSHIIIC
Transcripts ENSG00000116396
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoli;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID Q03721
HGNC ID HGNC:6236
VEGA ID OTTHUMG00000011037
OMIM ID 176265
String ID 9606.ENSP00000358802
Drugbank ID BE0003319; BE0009847
PharmGKB ID PA30028
Target gene [KCNC4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000414 chr1 11 426 45 482 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of KCNC4 expression and immune infiltrating cell level correlation result in HIV+ samples
KCNC4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).