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HBV Target gene Detail Information

> KCNC2 Gene Search Result


Gene Information
Gene Name KCNC2
Gene ID 3747
Gene Full Name potassium voltage-gated channel subfamily C member 2
Gene Alias KV3.2
Transcripts ENSG00000166006
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID Q96PR1
HGNC ID HGNC:6234
VEGA ID OTTHUMG00000169717
OMIM ID 176256
String ID 9606.ENSP00000449253
Drugbank ID BE0004724; BE0009847
PharmGKB ID PA35490
Target gene [KCNC2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012029 chr12 2 6 8 View
1016034 chr12 2 2 View
1016035 chr12 2 2 View
1016038 chr12 2 2 View
1016039 chr12 2 2 View
1016042 chr12 2 2 View
1016043 chr12 2 2 View
1016044 chr12 2 2 View
1016048 chr12 2 2 View
1016050 chr12 2 2 View
1016059 chr12 2 2 View
1016064 chr12 2 2 View
1016126 chr12 2 2 View
1019102 chr12 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNC2 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNC2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).