HBV Target gene Detail Information

> KCNAB1 Gene Search Result


Gene Information
Gene Name KCNAB1
Gene ID 7881
Gene Full Name potassium voltage-gated channel subfamily A member regulatory beta subunit 1
Gene Alias hKvb3; AKR6A3; KCNA1B; Kvb1.3; hKvBeta3; KV-BETA-1
Transcripts ENSG00000169282
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins, Transporters
Uniport_ID Q14722
HGNC ID HGNC:6228
VEGA ID OTTHUMG00000158552
OMIM ID 601141
String ID 9606.ENSP00000419952
Drugbank ID BE0010080; BE0009847
PharmGKB ID PA370
Target gene [KCNAB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002744 chr3 36 36 140 212 View
1006970 chr3 3 14 15 32 View
1404793 chr3 17 1 1 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNAB1 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNAB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).