HIV Target gene Detail Information

> KCMF1 Gene Search Result

Gene Information

Gene Name	KCMF1
Gene ID	56888
Gene Full Name	potassium channel modulatory factor 1
Gene Alias	FIGC; PCMF; ZZZ1; DEBT91
Transcripts	ENSG00000176407
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9P0J7
HGNC ID	HGNC:20589
VEGA ID	OTTHUMG00000153004
OMIM ID	614719
String ID	9606.ENSP00000386738
PharmGKB ID	PA134967694

Target gene [KCMF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001426	chr2	120	6	41	167	View
4009030	chr2	5	8		13	View
4010312	chr2		6	3	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KCMF1 expression and immune infiltrating cell level correlation result in HIV+ samples
KCMF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KCMF1 expression and immune infiltrating cell level correlation result in HIV+ samples
KCMF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).