HIV Target gene Detail Information

> KAT6A Gene Search Result

Gene Information

Gene Name	KAT6A
Gene ID	7994
Gene Full Name	lysine acetyltransferase 6A
Gene Alias	MOZ; MRD32; MYST3; MYST-3; ZNF220; RUNXBP2; ZC2HC6A
Transcripts	ENSG00000083168
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;Nucleoli;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	Q92794
HGNC ID	HGNC:13013
VEGA ID	OTTHUMG00000150453
OMIM ID	601408
String ID	9606.ENSP00000380136
PharmGKB ID	PA37592

Target gene [KAT6A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000176	chr8	18	563	239	820	View
4001155	chr8	49	79	76	204	View
4001824	chr8	7	13	109	129	View
4002037	chr8	77	31	8	116	View
4003410	chr8	62			62	View
4005746	chr8	27	3		30	View
4007418	chr8	14	5		19	View
4014029	chr8	1	2		3	View
4014243	chr8	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KAT6A expression and immune infiltrating cell level correlation result in HIV+ samples
KAT6A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).