HIV Target gene Detail Information

> KAT2B Gene Search Result

Gene Information

Gene Name	KAT2B
Gene ID	8850
Gene Full Name	lysine acetyltransferase 2B
Gene Alias	CAF; PCAF; P/CAF
Transcripts	ENSG00000114166
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q92831
HGNC ID	HGNC:8638
VEGA ID	OTTHUMG00000130481
OMIM ID	602303
String ID	9606.ENSP00000263754
Drugbank ID	BE0002683
PharmGKB ID	PA162392705

Target gene [KAT2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004347	chr3	45	1		46	View
4008617	chr3	8	6		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KAT2B expression and immune infiltrating cell level correlation result in HIV+ samples
KAT2B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KAT2B expression and immune infiltrating cell level correlation result in HIV+ samples
KAT2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).