HBV Target gene Detail Information

> JPH3 Gene Search Result


Gene Information
Gene Name JPH3
Gene ID 57338
Gene Full Name junctophilin 3
Gene Alias JP3; HDL2; JP-3; TNRC22; CAGL237
Transcripts ENSG00000154118
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted membrane proteins
Uniport_ID Q8WXH2
HGNC ID HGNC:14203
VEGA ID OTTHUMG00000137656
OMIM ID 605268
String ID 9606.ENSP00000284262
PharmGKB ID PA30000
Target gene [JPH3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011403 chr16 7 2 9 View
1011451 chr16 7 2 9 View
1011855 chr16 6 2 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of JPH3 expression and immune infiltrating cell level correlation result in HBV+ samples
JPH3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).