HIV Target gene Detail Information

> JOSD1 Gene Search Result

Gene Information

Gene Name	JOSD1
Gene ID	9929
Gene Full Name	Josephin domain containing 1
Gene Alias	dJ508I15.2
Transcripts	ENSG00000100221
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q15040
HGNC ID	HGNC:28953
VEGA ID	OTTHUMG00000151030
OMIM ID	615323
String ID	9606.ENSP00000216039
PharmGKB ID	PA142671644

Target gene [JOSD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001729	chr22	3	65	68	136	View
4006888	chr22	5	8	9	22	View
4006955	chr22	21	1		22	View
4010591	chr22	7	1		8	View
4011088	chr22	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of JOSD1 expression and immune infiltrating cell level correlation result in HIV+ samples
JOSD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of JOSD1 expression and immune infiltrating cell level correlation result in HIV+ samples
JOSD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).