HBV Target gene Detail Information

> JDP2 Gene Search Result

Gene Information

Gene Name	JDP2
Gene ID	122953
Gene Full Name	Jun dimerization protein 2
Gene Alias	JUNDM2
Transcripts	ENSG00000140044
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q8WYK2
HGNC ID	HGNC:17546
VEGA ID	OTTHUMG00000171869
OMIM ID	608657
String ID	9606.ENSP00000267569
Drugbank ID	BE0004853; BE0004924
PharmGKB ID	PA162392499

Target gene [JDP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002763	chr14	117	73	18	208	View
1002845	chr14	121	60	18	199	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of JDP2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
JDP2 expression: Low -> High
Lollipop of JDP2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of JDP2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of JDP2 expression and immune infiltrating cell level correlation result in HBV+ samples
JDP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).