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HBV Target gene Detail Information

> JAM3 Gene Search Result


Gene Information
Gene Name JAM3
Gene ID 83700
Gene Full Name junctional adhesion molecule 3
Gene Alias JAMC; JAM-2; JAM-3; JAM-C
Transcripts ENSG00000166086
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID Q9BX67
HGNC ID HGNC:15532
VEGA ID OTTHUMG00000167130
OMIM ID 606871
String ID 9606.ENSP00000299106
PharmGKB ID PA29993
Target gene [JAM3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008257 chr11 21 21 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of JAM3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
JAM3 expression: Low -> High
Lollipop of JAM3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of JAM3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of JAM3 expression and immune infiltrating cell level correlation result in HBV+ samples
JAM3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).