HIV Target gene Detail Information

> ITSN2 Gene Search Result

Gene Information

Gene Name	ITSN2
Gene ID	50618
Gene Full Name	intersectin 2
Gene Alias	SWA; SWAP; SH3D1B; SH3P18; PRO2015
Transcripts	ENSG00000198399
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NZM3
HGNC ID	HGNC:6184
VEGA ID	OTTHUMG00000090818
OMIM ID	604464
String ID	9606.ENSP00000347244
PharmGKB ID	PA29982

Target gene [ITSN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001310	chr2	170	10		180	View
4001964	chr2	16	25	79	120	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ITSN2 expression and immune infiltrating cell level correlation result in HIV+ samples
ITSN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).