HBV Target gene Detail Information

> ITSN1 Gene Search Result

Gene Information

Gene Name	ITSN1
Gene ID	6453
Gene Full Name	intersectin 1
Gene Alias	ITSN; SH3D1A; SH3P17
Transcripts	ENSG00000205726
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q15811
HGNC ID	HGNC:6183
VEGA ID	OTTHUMG00000065284
OMIM ID	602442
String ID	9606.ENSP00000370719
PharmGKB ID	PA29981

Target gene [ITSN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006700	chr21	6	9	20	35	View
1008323	chr21	17	4		21	View
1009197	chr21	15	2		17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITSN1 expression and immune infiltrating cell level correlation result in HBV+ samples
ITSN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).