HIV Target gene Detail Information

> ITPR3 Gene Search Result


Gene Information
Gene Name ITPR3
Gene ID 3710
Gene Full Name inositol 1,4,5-trisphosphate receptor type 3
Gene Alias IP3R; IP3R3
Transcripts ENSG00000096433
Virus HIV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins
Uniport_ID Q14573
HGNC ID HGNC:6182
VEGA ID OTTHUMG00000014532
OMIM ID 147267
String ID 9606.ENSP00000363435
Drugbank ID BE0004848; BE0004914
PharmGKB ID PA29980
Target gene [ITPR3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003500 chr6 50 10 60 View
4005955 chr6 19 8 1 28 View
4009002 chr6 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ITPR3 expression and immune infiltrating cell level correlation result in HIV+ samples
ITPR3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ITPR3 expression and immune infiltrating cell level correlation result in HIV+ samples
ITPR3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).