HBV Target gene Detail Information

> ITPR1 Gene Search Result

Gene Information

Gene Name	ITPR1
Gene ID	3708
Gene Full Name	inositol 1,4,5-trisphosphate receptor type 1
Gene Alias	ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94
Transcripts	ENSG00000150995
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q14643
HGNC ID	HGNC:6180
VEGA ID	OTTHUMG00000154996
OMIM ID	147265
String ID	9606.ENSP00000306253
Drugbank ID	BE0004522; BE0004914
PharmGKB ID	PA29978

Target gene [ITPR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013031	chr3	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITPR1 expression and immune infiltrating cell level correlation result in HBV+ samples
ITPR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).