HBV Target gene Detail Information

> ITPKC Gene Search Result


Gene Information
Gene Name ITPKC
Gene ID 80271
Gene Full Name inositol-trisphosphate 3-kinase C
Gene Alias IP3KC; IP3-3KC
Transcripts ENSG00000086544
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q96DU7
HGNC ID HGNC:14897
VEGA ID OTTHUMG00000182688
OMIM ID 606476
String ID 9606.ENSP00000263370
PharmGKB ID PA29977
Target gene [ITPKC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015940 chr19 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ITPKC expression and immune infiltrating cell level correlation result in HBV+ samples
ITPKC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).