HBV Target gene Detail Information

> ITPKB Gene Search Result

Gene Information

Gene Name	ITPKB
Gene ID	3707
Gene Full Name	inositol-trisphosphate 3-kinase B
Gene Alias	IP3K; IP3KB; PIG37; IP3K-B; IP3-3KB
Transcripts	ENSG00000143772
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	P27987
HGNC ID	HGNC:6179
VEGA ID	OTTHUMG00000037582
OMIM ID	147522
String ID	9606.ENSP00000411152
PharmGKB ID	PA29976

Target gene [ITPKB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010647	chr1	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITPKB expression and immune infiltrating cell level correlation result in HBV+ samples
ITPKB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).