HIV Target gene Detail Information

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Gene Information

Gene Name	ITK
Gene ID	3702
Gene Full Name	IL2 inducible T cell kinase
Gene Alias	EMT; LYK; LPFS1; PSCTK2
Transcripts	ENSG00000113263
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q08881
HGNC ID	HGNC:6171
VEGA ID	OTTHUMG00000130245
OMIM ID	186973
String ID	9606.ENSP00000398655
Drugbank ID	BE0001341
Drug (Cytoscape Annotation)	Sunitinib Malate
PharmGKB ID	PA29968

Target gene [ITK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006019	chr5	21	6		27	View
4011270	chr5	5	2		7	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).