HBV Target gene Detail Information

> ITGAV Gene Search Result

Gene Information

Gene Name	ITGAV
Gene ID	3685
Gene Full Name	integrin subunit alpha V
Gene Alias	CD51; MSK8; VNRA; VTNR
Transcripts	ENSG00000138448
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Focal adhesion sites;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Gene Function	Suppressor gene
Uniport_ID	P06756
HGNC ID	HGNC:6150
VEGA ID	OTTHUMG00000132635
OMIM ID	193210
String ID	9606.ENSP00000261023
Drugbank ID	BE0003576
PharmGKB ID	PA37336

Target gene [ITGAV] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008326	chr2	17	4		21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITGAV expression and immune infiltrating cell level correlation result in HBV+ samples
ITGAV expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).