HBV Target gene Detail Information

> ITGA10 Gene Search Result


Gene Information
Gene Name ITGA10
Gene ID 8515
Gene Full Name integrin subunit alpha 10
Gene Alias PRO827
Transcripts ENSG00000143127
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins
Uniport_ID O75578
HGNC ID HGNC:6135
VEGA ID OTTHUMG00000013751
OMIM ID 604042
String ID 9606.ENSP00000358310
PharmGKB ID PA29936
Target gene [ITGA10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1400432 chr1 403 14 3 420 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ITGA10 expression and immune infiltrating cell level correlation result in HBV+ samples
ITGA10 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).