HIV Target gene Detail Information

> ITFG2 Gene Search Result

Gene Information

Gene Name	ITFG2
Gene ID	55846
Gene Full Name	integrin alpha FG-GAP repeat containing 2
Gene Alias	FGGAP1; MDS028
Transcripts	ENSG00000111203
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Nucleoplasm;Cytokinetic bridge;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q969R8
HGNC ID	HGNC:30879
VEGA ID	OTTHUMG00000130617
OMIM ID	617421
String ID	9606.ENSP00000228799
PharmGKB ID	PA143485507

Target gene [ITFG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000037	chr12	826	703	317	1846	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ITFG2 expression and immune infiltrating cell level correlation result in HIV+ samples
ITFG2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ITFG2 expression and immune infiltrating cell level correlation result in HIV+ samples
ITFG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).