HIV Target gene Detail Information

> ISY1 Gene Search Result

Gene Information

Gene Name	ISY1
Gene ID	57461
Gene Full Name	ISY1 splicing factor homolog
Gene Alias	FSAP33
Transcripts	ENSG00000240682
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9ULR0
HGNC ID	HGNC:29201
VEGA ID	OTTHUMG00000137365
OMIM ID	612764
String ID	9606.ENSP00000273541
PharmGKB ID	PA162392343

Target gene [ISY1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012541	chr3	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ISY1 expression and immune infiltrating cell level correlation result in HIV+ samples
ISY1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ISY1 expression and immune infiltrating cell level correlation result in HIV+ samples
ISY1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).