HIV Target gene Detail Information

> IST1 Gene Search Result

Gene Information

Gene Name	IST1
Gene ID	9798
Gene Full Name	IST1, ESCRT-III associated factor
Gene Alias	OLC1
Transcripts	ENSG00000182149
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P53990
HGNC ID	HGNC:28977
VEGA ID	OTTHUMG00000137597
OMIM ID	616434
String ID	9606.ENSP00000438399
PharmGKB ID	PA142671633

Target gene [IST1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001960	chr16	111	10		121	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IST1 expression and immune infiltrating cell level correlation result in HIV+ samples
IST1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).