HBV Target gene Detail Information

> IQUB Gene Search Result

Gene Information

Gene Name	IQUB
Gene ID	154865
Gene Full Name	IQ motif and ubiquitin domain containing
Transcripts	ENSG00000164675
Virus	HBV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Nuclear speckles;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NA54
HGNC ID	HGNC:21995
VEGA ID	OTTHUMG00000157347
String ID	9606.ENSP00000417769
PharmGKB ID	PA162392258

Target gene [IQUB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003774	chr7	98	12		110	View
1401143	chr7	98	12		110	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IQUB expression and immune infiltrating cell level correlation result in HBV+ samples
IQUB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).