HTLV1 Target gene Detail Information

> IPO5 Gene Search Result


Gene Information
Gene Name IPO5
Gene ID 3843
Gene Full Name importin 5
Gene Alias IMB3; Pse1; imp5; KPNB3; RANBP5
Transcripts ENSG00000065150
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID O00410
HGNC ID HGNC:6402
VEGA ID OTTHUMG00000017244
OMIM ID 602008
String ID 9606.ENSP00000261574
PharmGKB ID PA30193
Target gene [IPO5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008556 chr13 37 1 6 44 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of IPO5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
IPO5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).