HBV Target gene Detail Information

> IPCEF1 Gene Search Result

Gene Information

Gene Name	IPCEF1
Gene ID	26034
Gene Full Name	interaction protein for cytohesin exchange factors 1
Gene Alias	PIP3-E
Transcripts	ENSG00000074706
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Plasma membrane;Cytoplasmic bodies;Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WWN9
HGNC ID	HGNC:21204
VEGA ID	OTTHUMG00000015872
String ID	9606.ENSP00000394751
PharmGKB ID	PA164721033

Target gene [IPCEF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000546	chr6	236	833	860	1929	View
1001644	chr6	48	272	233	553	View
1002253	chr6	177	118	10	305	View
1002254	chr6	177	118	10	305	View
1002255	chr6	177	118	10	305	View
1002256	chr6	177	118	10	305	View
1002257	chr6	177	118	10	305	View
1002258	chr6	177	118	10	305	View
1002259	chr6	177	118	10	305	View
1002260	chr6	177	118	10	305	View
1002317	chr6	177	108	9	294	View
1002366	chr6	175	102	9	286	View
1402346	chr6	48	272	233	553	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IPCEF1 expression and immune infiltrating cell level correlation result in HBV+ samples
IPCEF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).