HIV Target gene Detail Information

> IP6K2 Gene Search Result

Gene Information

Gene Name	IP6K2
Gene ID	51447
Gene Full Name	inositol hexakisphosphate kinase 2
Gene Alias	PIUS; IHPK2
Transcripts	ENSG00000068745
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;Cell Junctions;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9UHH9
HGNC ID	HGNC:17313
VEGA ID	OTTHUMG00000133543
OMIM ID	606992
String ID	9606.ENSP00000331103
PharmGKB ID	PA164720999

Target gene [IP6K2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000741	chr3	9	258	29	296	View
4002388	chr3	24	55	17	96	View
4004735	chr3	40			40	View
4005986	chr3	4	14	10	28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IP6K2 expression and immune infiltrating cell level correlation result in HIV+ samples
IP6K2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IP6K2 expression and immune infiltrating cell level correlation result in HIV+ samples
IP6K2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).