HIV Target gene Detail Information

> IP6K1 Gene Search Result

Gene Information

Gene Name	IP6K1
Gene ID	9807
Gene Full Name	inositol hexakisphosphate kinase 1
Gene Alias	PiUS; IHPK1
Transcripts	ENSG00000176095
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q92551
HGNC ID	HGNC:18360
VEGA ID	OTTHUMG00000158197
OMIM ID	606991
String ID	9606.ENSP00000482032
PharmGKB ID	PA164720982

Target gene [IP6K1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001947	chr3	95	26		121	View
4002733	chr3	77	5		82	View
4003511	chr3	52	5	3	60	View
4003954	chr3	12	37	3	52	View
4009571	chr3	10	1		11	View
4009961	chr3	8	2		10	View
4010245	chr3	3	6		9	View
4010872	chr3	6	2		8	View
4014281	chr3	2			2	View
4014459	chr3	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IP6K1 expression and immune infiltrating cell level correlation result in HIV+ samples
IP6K1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IP6K1 expression and immune infiltrating cell level correlation result in HIV+ samples
IP6K1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).