MCV Target gene Detail Information

> INPP5E Gene Search Result


Gene Information
Gene Name INPP5E
Gene ID 56623
Gene Full Name inositol polyphosphate-5-phosphatase E
Gene Alias CPD4; CORS1; JBTS1; MORMS; PPI5PIV; pharbin
Transcripts ENSG00000148384
Virus MCV
Gene Type protein coding
HPA Location Info Focal adhesion sites;Golgi apparatus;Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9NRR6
HGNC ID HGNC:21474
VEGA ID OTTHUMG00000020927
OMIM ID 613037
String ID 9606.ENSP00000360777
PharmGKB ID PA164741785
Target gene [INPP5E] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
7300008 chr9 7685 6549 1903 16137 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE50451-GPL571 (GEO) Merkel cell carcinoma 50 Merkel cell carcinoma (MCV+)(16), Merkel cell carcinoma (MCV-)(7), Merkel cell carcinoma cell line (MCV+)(1), Merkel cell carcinoma cell line MCC13 (MCV-)(3), Merkel cell carcinoma cell line MCC26 (MCV-)(3), Merkel cell carcinoma cell line Mkl-1 (MCV+)(6), Merkel cell carcinoma cell lineUISO(MCV-)(7), Merkel cell carcinoma cell line WaGa (MCV+)(7)

> Dataset: GSE50451-GPL571

HeatMap of cell type fractions in all samples Lollipop of INPP5E expression and immune infiltrating cell level correlation result in MCV+ samples
INPP5E expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).