HIV Target gene Detail Information

> INO80 Gene Search Result


Gene Information
Gene Name INO80
Gene ID 54617
Gene Full Name INO80 complex subunit
Gene Alias INOC1; INO80A
Transcripts ENSG00000128908
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;Cytosol;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9ULG1
HGNC ID HGNC:26956
VEGA ID OTTHUMG00000130209
OMIM ID 610169
String ID 9606.ENSP00000355205
PharmGKB ID PA162392040
Target gene [INO80] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006265 chr15 24 2 26 View
4008145 chr15 12 4 16 View
4009137 chr15 10 2 12 View
4012060 chr15 3 2 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of INO80 expression and immune infiltrating cell level correlation result in HIV+ samples
INO80 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of INO80 expression and immune infiltrating cell level correlation result in HIV+ samples
INO80 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).