HIV Target gene Detail Information

> ING3 Gene Search Result

Gene Information

Gene Name	ING3
Gene ID	54556
Gene Full Name	inhibitor of growth family member 3
Gene Alias	Eaf4; ING2; MEAF4; p47ING3
Transcripts	ENSG00000071243
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9NXR8
HGNC ID	HGNC:14587
VEGA ID	OTTHUMG00000141270
OMIM ID	607493
String ID	9606.ENSP00000320566
PharmGKB ID	PA29875

Target gene [ING3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006012	chr7	14	5	9	28	View
4012166	chr7	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ING3 expression and immune infiltrating cell level correlation result in HIV+ samples
ING3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ING3 expression and immune infiltrating cell level correlation result in HIV+ samples
ING3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).