HPV Target gene Detail Information

> IMPG2 Gene Search Result

Gene Information

Gene Name	IMPG2
Gene ID	50939
Gene Full Name	interphotoreceptor matrix proteoglycan 2
Gene Alias	RP56; VMD5; IPM200; SPACRCAN
Transcripts	ENSG00000081148
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q9BZV3
HGNC ID	HGNC:18362
VEGA ID	OTTHUMG00000159091
OMIM ID	607056
String ID	9606.ENSP00000193391
Drugbank ID	BE0004877; BE0004942
PharmGKB ID	PA29866

Target gene [IMPG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402405	chr3		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of IMPG2 expression and immune infiltrating cell level correlation result in HPV+ samples
IMPG2 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of IMPG2 expression and immune infiltrating cell level correlation result in HPV+ samples
IMPG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).