HIV Target gene Detail Information

> ILK Gene Search Result

Gene Information

Gene Name	ILK
Gene ID	3611
Gene Full Name	integrin linked kinase
Gene Alias	P59; ILK-1; ILK-2; p59ILK; HEL-S-28
Transcripts	ENSG00000166333
Virus	HIV
Gene Type	protein coding
HPA Location Info	Focal adhesion sites;Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene & Oncogene
Uniport_ID	Q13418
HGNC ID	HGNC:6040
VEGA ID	OTTHUMG00000133407
OMIM ID	602366
String ID	9606.ENSP00000379975
PharmGKB ID	PA29855

Target gene [ILK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000014	chr11	2390	243	247	2880	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ILK expression and immune infiltrating cell level correlation result in HIV+ samples
ILK expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ILK expression and immune infiltrating cell level correlation result in HIV+ samples
ILK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).