HTLV1 Target gene Detail Information

> IL9R Gene Search Result


Gene Information
Gene Name IL9R
Gene ID 3581
Gene Full Name interleukin 9 receptor
Gene Alias CD129; IL-9R
Transcripts ENSG00000124334
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Predicted membrane proteins
Uniport_ID Q01113
HGNC ID HGNC:6030
VEGA ID OTTHUMG00000022720
OMIM ID 300007
String ID 9606.ENSP00000244174
PharmGKB ID PA29846
Target gene [IL9R] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6100347 chrX 179 114 82 375 View
6100348 chrX 18 4 23 45 View
6100349 chrX 56 3 2 61 View
6100353 chrY 0 View
6100354 chrY 0 View
6100355 chrY 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of IL9R expression and immune infiltrating cell level correlation result in HTLV1+ samples
IL9R expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of IL9R expression and immune infiltrating cell level correlation result in HTLV1+ samples
IL9R expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of IL9R expression and immune infiltrating cell level correlation result in HTLV1+ samples
IL9R expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).