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HBV Target gene Detail Information

> IL1R1 Gene Search Result


Gene Information
Gene Name IL1R1
Gene ID 3554
Gene Full Name interleukin 1 receptor type 1
Gene Alias P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha
Transcripts ENSG00000115594
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;Cytosol;Plasma membrane;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters
Uniport_ID P14778
HGNC ID HGNC:5993
VEGA ID OTTHUMG00000130783
OMIM ID 147810
String ID 9606.ENSP00000386380
Drugbank ID BE0000565
PharmGKB ID PA29809
Target gene [IL1R1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010923 chr2 1 8 1 10 View
1402883 chr2 1 8 1 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of IL1R1 expression and immune infiltrating cell level correlation result in HBV+ samples
IL1R1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).