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HBV Target gene Detail Information

> IL1B Gene Search Result


Gene Information
Gene Name IL1B
Gene ID 3553
Gene Full Name interleukin 1 beta
Gene Alias IL-1; IL1F2; IL1-BETA
Transcripts ENSG00000125538
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters
Uniport_ID P01584
HGNC ID HGNC:5992
VEGA ID OTTHUMG00000131344
OMIM ID 147720
String ID 9606.ENSP00000263341
Drugbank ID BE0001051
PharmGKB ID PA29808
Target gene [IL1B] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 30404796 G1896A
PreC
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of IL1B expression and immune infiltrating cell level correlation result in HBV+ samples
IL1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).