HIV Target gene Detail Information

> IL17RA Gene Search Result

Gene Information

Gene Name	IL17RA
Gene ID	23765
Gene Full Name	interleukin 17 receptor A
Gene Alias	CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R
Transcripts	ENSG00000177663
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Predicted to be secreted;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	Q96F46
HGNC ID	HGNC:5985
VEGA ID	OTTHUMG00000150026
OMIM ID	605461
String ID	9606.ENSP00000320936
PharmGKB ID	PA29801

Target gene [IL17RA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003731	chr22	7	48		55	View
4012482	chr22	4		1	5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IL17RA expression and immune infiltrating cell level correlation result in HIV+ samples
IL17RA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IL17RA expression and immune infiltrating cell level correlation result in HIV+ samples
IL17RA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).