HIV Target gene Detail Information

> IL12RB2 Gene Search Result

Gene Information

Gene Name	IL12RB2
Gene ID	3595
Gene Full Name	interleukin 12 receptor subunit beta 2
Transcripts	ENSG00000081985
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q99665
HGNC ID	HGNC:5972
VEGA ID	OTTHUMG00000009094
OMIM ID	601642
String ID	9606.ENSP00000262345
PharmGKB ID	PA29787

Target gene [IL12RB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007342	chr1	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IL12RB2 expression and immune infiltrating cell level correlation result in HIV+ samples
IL12RB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IL12RB2 expression and immune infiltrating cell level correlation result in HIV+ samples
IL12RB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).