HBV Target gene Detail Information

> IL12B Gene Search Result

Gene Information

Gene Name	IL12B
Gene ID	3593
Gene Full Name	interleukin 12B
Gene Alias	CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
Transcripts	ENSG00000113302
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID	P29460
HGNC ID	HGNC:5970
VEGA ID	OTTHUMG00000130307
OMIM ID	161561
String ID	9606.ENSP00000231228
Drugbank ID	BE0000981; BE0008663
PharmGKB ID	PA29785
FDA Approved Drug	Ustekinumab

Target gene [IL12B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1019627	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IL12B expression and immune infiltrating cell level correlation result in HBV+ samples
IL12B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).