HIV Target gene Detail Information

> IL10RA Gene Search Result

Gene Information

Gene Name	IL10RA
Gene ID	3587
Gene Full Name	interleukin 10 receptor subunit alpha
Gene Alias	CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Transcripts	ENSG00000110324
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, Predicted membrane proteins
Uniport_ID	Q13651
HGNC ID	HGNC:5964
VEGA ID	OTTHUMG00000166523
OMIM ID	146933
String ID	9606.ENSP00000227752
PharmGKB ID	PA29779

Target gene [IL10RA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005814	chr11	29			29	View
4009802	chr11	9	1		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IL10RA expression and immune infiltrating cell level correlation result in HIV+ samples
IL10RA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IL10RA expression and immune infiltrating cell level correlation result in HIV+ samples
IL10RA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).